Int J Clin Pharm Th
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Int J Clin Pharm Th · Oct 2010
Randomized Controlled TrialA thorough QT/QTc study of multiple doses of tapentadol immediate release in healthy subjects.
This randomized, double-blind, placebo- and positive-controlled 4-way crossover study evaluated the effects of tapentadol immediate release (IR) on the QT/QTc interval. ⋯ Therapeutic and supratherapeutic doses of tapentadol do not affect the QT/QTc interval.