Int J Clin Pharm Th

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• Int J Clin Pharm Th · Mar 2018

  Randomized Controlled Trial Comparative Study

  Comparison of the treatment efficacy between tigecycline plus high-dose cefoperazone-sulbactam and tigecycline monotherapy against ventilator-associated pneumonia caused by extensively drug-resistant Acinetobacter baumannii.

  The present study examined the effect of high-dose cefoperazone-sulbactam combined with tigecycline against ventilator-associated pneumonia (VAP) caused by extensively drug-resistant Acinetobacter baumannii(XDR-AB). ⋯ High dose of cefoperazone-sulbactam can improve the antimicrobial activity of tigecycline against XDR-AB.
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