Pharm World Sci
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To describe clozapine prescribing in a mental health service in Auckland, New Zealand and compare it with national and international treatment guidelines. ⋯ Contemporary management of patients with treatment resistant schizophrenia in New Zealand is broadly in line with national and international best practice guidelines. There is some evidence, based on hospitalisation rates, to support the assertion that shorter delays in accessing clozapine leads to better outcomes. This needs further evaluation using measures of clinical outcome including objective measures of functioning.
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This is a retrospective study, based on analysis of data from patients with previous adverse drug reactions admitted to the Allergy and Clinical Immunology Division of both the University of Messina and the University of Bari in the last 4 years. We observed five patients: four of them (two males and two females) with a well documented history of tranexamic acid hypersensitivity reactions and one female who showed a positive response to an intradermal challenge test with tranexamic acid. ⋯ Although the risk of immunogenic and severe allergic reactions to tranexamic acid is significantly lower than those associated with administration of other drugs, our experience points out that adverse reactions to tranexamic acid can occur. This drug may be responsible for a wide and various spectrum of hypersensitivity reactions characterized by different pathogenetic mechanisms (immunologic and non-immunologic). Etamsylate was a well tolerated alternative drug to tranexamic acid in all examined patients.
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Comparative Study
A self-reported work-sampling study in community pharmacy practice: a 2009 update.
Using a self-reported work sampling methodology this study investigated how community pharmacists utilised their time, and quantified how much time pharmacists devoted to specific activities. ⋯ Pharmacists in this study are spending more time checking prescriptions (essential component of pharmaceutical care) and are still managing to spend only 20% of their time on non-professional activities. However, there had been relatively little change in the way in which pharmacists in this sample spent their time compared to a previous study.