The Journal of surgical research
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In acutely anephric dogs, depressed reflex adrenal medullary secretion (AMS) may be related to low plasma angiotensin. Either local (adrenal medulla) or central nervous system mechanisms are responsible. Local influences of acute bilateral nephrectomy on AMS were evaluated after left splanchnic nerve section. ⋯ At the first stimulation interval NE:E was 0.28 +/- 0.14 (1 SD) in renal intact dogs vs 0.11 +/- 0.04 in anephric dogs, P less than 0.05. At rest NE:E was 0.33 +/- 0.12 in group 1 vs 0.17 +/- 0.02 in group 2 dogs, P less than 0.02. Plasma NE was also low in the anephric group (289 mg/liter +/- 126 (1 SD) vs 612 +/- 189, P = 0.033, resting).(ABSTRACT TRUNCATED AT 250 WORDS)
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Subcritical iliac artery stenoses become critical stenoses if common femoral artery (CFA) flow rates increase sufficiently. Infrainguinal bypasses done in the presence of subcritical iliac artery stenoses may be in jeopardy on the basis of inadequate inflow if critical iliac stenoses are produced by increased CFA flow resulting from the bypasses. This study was undertaken to define the CFA hemodynamic changes seen with femoropopliteal bypass and to determine the relative effects of subcritical iliac artery stenoses on these pressure and flow changes. ⋯ Despite these increases in CFA flow, CFA pressure indices were unchanged when comparing open with occluded SFAs even in the presence of subcritical iliac artery stenoses. These findings suggest that femoropopliteal bypass does not result in increases in CFA flow rates sufficient enough to cause decreased graft perfusion pressures in the presence of subcritical iliac artery stenoses. Therefore, the patency of an infrainguinal bypass done in the presence of a subcritical iliac artery stenosis should not be adversely affected in the early postoperative period on the basis of inflow.