The Journal of surgical research
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Currently, accurate measurements of extravascular lung water (EVLW) are obtained using the double dye dilution technique (DD). However, this method is invasive and complicated and has limited its clinical use. The purpose of this study was to develop a noninvasive method for determining changes in EVLW using bioimpedance (BI) and compare these measurements with DD in a model of acute pulmonary injury. ⋯ There was no difference in computed EVLW using DD and BI at 15, 30, and 60 min following oleic acid infusion (P greater than 0.35). CO was significantly correlated using DD and BI (r = 0.81, P less than 0.05). In summary, bioimpedance may hold promise as a noninvasive and continuous means for estimation of EVLW in the critical care setting.