Zh Nevrol Psikhiatr
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Zh Nevrol Psikhiatr · Jan 2020
Biography Historical Article[P.E. Flechsig's contribution to a Russian-German scientific exchange in the fields of neuropathology and psychiatry].
The University of Leipzig has played an important role in the Russian-German scientific exchange in the fields of psychiatry and neurology in the 19th century. An outstanding but almost forgotten protagonist of that exchange was the psychiatrist and neurologist Paul Flechsig, who enjoyed worldwide recognition for his neuroanatomical works. Famous Russian neurologists and psychiatrists as Vladimir Bekhterev, Liverij Osipovich Darkshevich, Vladimir Chizh not only learned from Flechsig's experience, but also undertook independent research, which gave them impulses for furthering their carriers in Russia.
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Zh Nevrol Psikhiatr · Jan 2020
[Mechanisms of changes in the spinal segmental level in patients with post-traumatic cervical myelopathy].
To study the neurophysiological mechanisms of motor deficit in patients with post-traumatic cervical myelopathy. ⋯ The main neurophysiological mechanisms of motor deficit in patients with post-traumatic cervical myelopathy are the combination of the primary neuronal damage at the level of spinal cord injury and the development of secondary axonal neuropathy more caudally at the first three years after spinal cord injury.
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Zh Nevrol Psikhiatr · Jan 2020
[General and primary incidence of mental disorders and their structure in people referred for support to the medical facilities of internal affairs organizations].
To analyze the structure of the incidence of mental disorders of persons attached to medical support to the medical units of the Ministry of Internal Affairs of Russia (MCH MIA) for the period 2013-2018. ⋯ The majority of mental disorders are neurotic, stress-related and somatoform disorders, which, with timely diagnosis and comprehensive treatment, can be fully treated.
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Zh Nevrol Psikhiatr · Jan 2019
Review[Evaluation of serum neurofilament light chains levels for diagnosis, treatment monitoring and prognosis in multiple sclerosis].
Pathophysiological processes in multiple sclerosis frequently not diagnosed by clinicians become available for analysis only on the basis of paraclinical data (biomarkers). Nowadays neurofilament light chain can be defined as a promising biomarker for multiple sclerosis (MS). Neurofilaments are a structural part of normal neuronal processes consisting of light, intermediate and heavy chains. ⋯ Cutting-edge highly sensitive methods make it possible to detect neurofilament light chains not only in the cerebrospinal fluid but also in the blood serum thus opening the opportunities to utilize them in routine diagnosis in clinical practice. This review comprises existing data on the possible opportunities for research of serum neurofilament light chains in terms of exacerbations, effectiveness of basic therapy, assessment of individual disability, the atrophy of central nervous system structures. Also, there is some information on comparison of two methods: routine MRI of the brain with the contrast agents and detection of serum neurofilament light chains.
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Zh Nevrol Psikhiatr · Jan 2019
[Neurostimulation of the supraorbital nerve with the Cefaly device - a new method for the treatment of migraine].
Treatment of migraine mainly includes pharmacological approaches aimed at breaking migraine attacks and preventive treatment to reduce their frequency. Despite the wide range of pharmacological agents, frequent side effects and pharmacotherapy resistance in patients with migraine determine the urgency of finding new alternative treatment strategies. ⋯ Stimulation of the supraorbital nerve with the percutaneous Cefaly device ('Cefaly Technology sprl', Seraing, Belgium) in clinical randomized, controlled studies has demonstrated efficacy in significantly reducing both the frequency of migraine attacks and the total number of days with headache. Cefaly is the first FDA approved migraine prevention medical device.