Ann Oto Rhinol Laryn
-
Ann Oto Rhinol Laryn · May 2009
Laryngopharyngeal reflux with sore throat: an ultrastructural study of oropharyngeal epithelium.
We performed an electron microscopic ultrastructural study of oropharyngeal epithelium in patients with laryngopharyngeal reflux (LPR) and sore throat to evaluate whether dilatation of intercellular spaces could be traced at this level. ⋯ Dilatation of intercellular spaces as a morphological marker can be traced in patients with LPR and sore throat at the level of the oropharynx. This contributes to a better understanding of the pathophysiology of LPR. If this finding is confirmed in a large series, it will represent a cost-effective, relatively noninvasive method for diagnosis of LPR.