The Journal of pharmacy and pharmacology

The most recent articles from: J. Pharm. Pharmacol. November 2017

J. Pharm. Pharmacol. · Nov 2017

Comparative Study

Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability.

This study was aimed to investigate the potential of formulated valproic acid-encapsulated nanoemulsion (VANE) to improve the brain bioavailability of valproic acid (VPA). ⋯ Nanoemulsion containing VPA has alleviated the cytotoxic effect of VPA and improved the plasma and brain bioavailability for parenteral delivery of VPA.

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