Plos One
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Rapid and extensive testing of large parts of the population and specific subgroups is crucial for proper management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and decision-making in times of a pandemic outbreak. However, point-of-care (POC) testing in places such as emergency units, outpatient clinics, airport security points or the entrance of any public building is a major challenge. The need for thermal cycling and nucleic acid isolation hampers the use of standard PCR-based methods for this purpose. ⋯ In summary, this approach reveals one-step multiplexed RT-LAMP assays as a prime-option for the development of easy and cheap POC test kits.
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In the global context, health and the quality of life of people are adversely affected by either one or more types of chronic diseases. This paper investigates the differences in the level of income and expenditure between chronically-ill people and non-chronic population. Data were gathered from a national level survey conducted namely, the Household Income and Expenditure Survey (HIES) by the Department of Census and Statistics (DCS) of Sri Lanka. ⋯ Considering private-public sector partnerships that enable affordable access to health care services for all as well as implementation of commercial insurance and community-based mutual services that help ease burden to the public, are vital when formulating effective policies and strategies related to the healthcare sector. Sri Lanka is making strong efforts to support its healthcare sector and public, which was affected by the coronavirus (COVID-19) in early 2020. Therefore, findings of this paper will be useful to gain insights on the differences of chronic illnesses towards the income and expenditure of chronically-ill patients in Sri Lanka.
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Allowing members of the crowd to propose novel microtasks for one another is an effective way to combine the efficiencies of traditional microtask work with the inventiveness and hypothesis generation potential of human workers. However, microtask proposal leads to a growing set of tasks that may overwhelm limited crowdsourcer resources. Crowdsourcers can employ methods to utilize their resources efficiently, but algorithmic approaches to efficient crowdsourcing generally require a fixed task set of known size. ⋯ Cost forecasting allows the crowdsourcer to decide between eliciting new tasks from the crowd or receiving responses to existing tasks based on whether or not new tasks will cost less to complete than existing tasks, efficiently balancing resources as crowdsourcing occurs. Experiments with real and synthetic crowdsourcing data show that cost forecasting leads to improved accuracy. Accuracy and efficiency gains for crowd-generated microtasks hold the promise to further leverage the creativity and wisdom of the crowd, with applications such as generating more informative and diverse training data for machine learning applications and improving the performance of user-generated content and question-answering platforms.
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Residency applications via virtual-interview could potentially mitigate the extensive cost and time required for customary in-person interviews. We outline the perception of medical students and residents on the use of virtual-interview for residency applications in lieu of in-person interviews. ⋯ In-person interviews are favored by both medical students and residents compared to virtual-interview services in normal circumstances. However, both groups agree that programs should offer the option of having virtual-interviews as an available choice. Distance to an interview location and the type of medical school were the factors that had a significant impact on perception of using virtual-interviews. Knowing about the applicants' attitude toward residency interviews and the national circumstances are essential when preparing the interview guides. Our findings are limited by the small sample size and the low response rate. Further extensive studies are warranted to better understand the perception of residency applicants toward virtual-interviews to improve the interview process in the United States.
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Information and Communication Technology (ICT) has been a key agent of change in the 21st century. Given the role of ICT in changing society, this research explores the responses and attitudes to change over time from ICT professionals and ICT academics in dealing with the potentially far reaching political challenge triggered by the UK's 2016 European Union Referendum and its decision to leave the European Union (Brexit). Whilst the vote was a UK based decision its ramifications have global implications and as such the research was not confined to the UK. This article presents the second phase of the research at the mid-point in the UK/European Union (EU) Brexit process, thus complementing the findings gathered immediately after the Referendum decision. The fundamental question being researched was: What are ICT professionals' personal and professional perspectives on the change triggered by Brexit in terms of opportunities and threats? ⋯ Data was collected through a survey launched in March 2018, one year on from the UK's triggering of Article 50 and marking the mid-point in the two-year Brexit process. The survey replicated the one delivered at the point of the Referendum decision in 2016 with some developments. In addition, two appreciative inquiry focus groups were conducted. The research sought to understand any shifting perspectives on the opportunities and threats that would exist post-Brexit for ICT professionals and academics. 59% of survey participants were negative regarding the Brexit decision. Participants noted the position post-Brexit for the UK, and the remaining 27 EU Member States (EU27), was still very uncertain at this stage. They observed that planned change versus uncertainty provides for very different responses. In spite of the uncertainty, the participants were able to consider and advocate for potential opportunities although these were framed from national perspectives. The opportunities identified within the appreciative inquiry focus groups aligned to those recorded by survey participants with similar themes highlighted. However, the optimum conditions for change have yet to be reached as there is still not an informed position, message and clear leadership with detailed information for the ICT context. Further data will be gathered after the UK exit from the EU, assuming this occurs.