Pediatrics
-
Randomized Controlled Trial
Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial.
To test the efficacy of Lactobacillus reuteri on infantile colic and to evaluate its relationship to the gut microbiota. ⋯ L. reuteri DSM 17 938 at a dose of 10(8) colony-forming units per day in early breastfed infants improved symptoms of infantile colic and was well tolerated and safe. Gut microbiota changes induced by the probiotic could be involved in the observed clinical improvement.