Jpen Parenter Enter
-
Jpen Parenter Enter · Mar 2006
Randomized Controlled TrialAntioxidant supplementation with or without B-group vitamins after acute ischemic stroke: a randomized controlled trial.
Evidence shows that there is a rapid increase in the production of markers of oxidative damage immediately after acute ischemic stroke and that endogenous antioxidant defenses are rapidly depleted, thus permitting further tissue damage. Several studies point to an antioxidant effect of B-group vitamins and a pro-oxidant effect of elevated total plasma homocysteine (tHcy). ⋯ Antioxidants supplementation with or without B-group vitamins enhances antioxidant capacity, mitigates oxidative damage, and may have an anti-inflammatory effect immediately postinfarct in stroke disease.