Pediatr Ann
-
SE is a common neurologic emergency in children. The majority of children who present in SE have no history of epilepsy. Although the clinical outcome of SE depends on the etiology of the seizure to a great extent, timely and appropriate treatment significantly reduces morbidity and mortality. ⋯ Achieving these four goals will improve the outcome of SE in all children. Future drug trials may also consider concurrent treatment with AEDs, which prevent the later development of epilepsy. In addition, neuroprotectants to protect against cell injury, lowering the morbidity and mortality associated with SE, and medications or rehabilitation strategies to improve the morbidity of SE after hospital discharge should also be studied.