Pediatr Crit Care Me
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Pediatr Crit Care Me · Mar 2008
Surgery-related posttraumatic stress disorder in parents of children undergoing cardiopulmonary bypass surgery: a prospective cohort study.
We aimed at evaluating surgery-related posttraumatic stress disorder (PTSD) in parents of children undergoing cardiopulmonary bypass surgery. Risk factors for parental PTSD symptoms were explored. ⋯ Parents of children undergoing cardiopulmonary bypass surgery are at increased risk for intermediate and long-term psychological malfunctioning. Acute symptoms of PTSD in parents shortly after discharge of their child are a major risk factor for the development of chronic PTSD. Clinicians need to identify parents at risk at an early stage to provide them with systematic support.
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Pediatr Crit Care Me · Mar 2008
Prospective detection of hyperglycemia in critically ill children using continuous glucose monitoring.
To evaluate the extent of hyperglycemia in nondiabetic children admitted to a pediatric intensive care unit using an interstitial continuous glucose monitor, and to compare the ability of this interstitial continuous glucose monitoring system to detect hyperglycemia with that of intermittent laboratory monitoring. ⋯ Significant hyperglycemia is present in pediatric intensive care patients and may be underestimated by intermittent laboratory monitoring.
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Pediatr Crit Care Me · Mar 2008
Editorial CommentOdds ratios, and odd musings, about neonatal septic shock.
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Pediatr Crit Care Me · Mar 2008
Randomized Controlled TrialCombination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children.
Recombinant human growth hormone (rhGH) is a salutary modulator of posttraumatic metabolic responses. However, rhGH administration is associated with deleterious side effects, such as hyperglycemia, increased free fatty acids, and triglycerides, which limit its use. Administration of beta-blocker attenuates cardiac work and resting energy expenditure after severe thermal injury and improves fat metabolism and insulin sensitivity. Therefore, the combination of rhGH plus propranolol appears ideal. The aim of the present study was to determine whether rhGH plus propranolol improves hypermetabolism and the inflammatory and acute phase response after severe burn without causing adverse side effects. ⋯ rhGH in combination with propranolol attenuates hypermetabolism and inflammation without the adverse side effects found with rhGH therapy alone.
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Pediatr Crit Care Me · Mar 2008
ReviewTherapeutic applications and uses of inhalational anesthesia in the pediatric intensive care unit.
To review the physical properties, end-organ effects, therapeutic applications, and delivery techniques of inhalational anesthetic agents in the pediatric intensive care unit. ⋯ The literature contains reports of the therapeutic use of the potent inhalational anesthetic agents in the pediatric intensive care unit. Potential applications include sedation during mechanical ventilation as well as therapeutic use for the treatment of status asthmaticus and epilepticus.