Pediatr Crit Care Me
-
Pediatr Crit Care Me · Jan 2011
Safety and efficacy of intravenous labetalol for hypertensive crisis in infants and small children.
To determine the efficacy and safety of labetalol for hypertensive crisis in children ≤ 24 months of age. ⋯ Continuous intravenous labetalol infusion is efficacious for treatment of hypertensive crisis in children ≤ 24 months of age. Aside from patients presenting with ischemic or traumatic brain injury, labetalol was safe to use in this population for hypertensive emergencies and had a satisfactory adverse effect profile. Labetalol may reach dose saturation at a much lower dose in young children in comparison to adults. Clinicians should use caution when initiating labetalol infusions in young patients with brain injury.
-
To provide a comprehensive review of dengue, with an emphasis on clinical syndromes, classification, diagnosis, and management, and to outline relevant aspects of epidemiology, immunopathogenesis, and prevention strategies. Dengue, a leading cause of childhood mortality in Asia and South America, is the most rapidly spreading and important arboviral disease in the world and has a geographic distribution of > 100 countries. ⋯ Dengue is no longer confined to the tropics and is a global disease. Treatment is supportive. Outcomes can be optimized by early recognition and cautious titrated fluid replacement, especially in resource-limited environments.
-
Pediatr Crit Care Me · Jan 2011
Noninvasive ventilation in a tertiary pediatric intensive care unit in a middle-income country.
To determine the factors that predict outcome of noninvasive ventilation (NIV) in critically ill children. ⋯ NIV was a feasible strategy of respiratory support to avoid intubation in > 75% of children in this study. A higher Pediatric Risk of Mortality II score, sepsis at initiation of NIV, an abnormal respiratory rate, and a higher requirement of Fio2 may be predictive factors of NIV failure.