Pediatr Crit Care Me
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Pediatr Crit Care Me · Jun 2019
Randomized Controlled Trial Multicenter StudyCardiac Arrest Outcomes in Children With Preexisting Neurobehavioral Impairment.
To describe survival and 3-month and 12-month neurobehavioral outcomes in children with preexisting neurobehavioral impairment enrolled in one of two parallel randomized clinical trials of targeted temperature management. ⋯ This study demonstrates the feasibility, utility, and challenge of including this population in clinical neuroprotection trials. In children with preexisting neurobehavioral impairment, one-third survived to 12 months and their neurobehavioral outcomes varied broadly.