Pediatr Crit Care Me
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Pediatr Crit Care Me · Nov 2020
The Role of Therapeutic Plasma Exchange in the Treatment of Childhood Intoxication: A Single-Center Experience.
Therapeutic plasma exchange is used to treat neurologic, hematological, renal, and autoimmune diseases with a known or suspected etiopathogenesis. However, there is incomplete understanding of the use of therapeutic plasma exchange in pediatric cases of intoxication. This study investigated 5 years of experience with therapeutic plasma exchange to treat intoxication cases. ⋯ Therapeutic plasma exchange appears to be safe and effective for treating pediatric cases of intoxication, including multidrug and amitriptyline intoxication, and is associated with significant recovery in the majority of severely affected patients. Treatment of intoxication with therapeutic plasma exchange should be guided primarily by the properties of the causative toxic substances/drugs, and consideration of patient age, the severity of clinical symptoms, Pediatric Logistic Organ Dysfunction score and response to initial supportive and antidotal treatment.
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Pediatr Crit Care Me · Nov 2020
Editorial CommentPediatric Sepsis in the Time of Coronavirus Disease 2019.
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Pediatr Crit Care Me · Nov 2020
eStablish And Formalize Expert Criteria for Avoidable Resuscitation Review (SAFECARR) Electronic Delphi: Development of a Consensus Framework for Classifying and Reviewing Cardiac Arrests Within the PICU.
To develop a consensus framework that can guide the process of classifying and reviewing pediatric in-hospital cardiac arrest in the PICU. ⋯ A multidisciplinary group of pediatric resuscitation experts generated a consensus-based framework to classify and review pediatric in-hospital cardiac arrest in the PICU. Future work will focus on the application of this framework and further validation of these definitions and contributing factors for in-hospital cardiac arrest both within and outside the PICU.
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Pediatr Crit Care Me · Nov 2020
Editorial CommentCan Computer Decision Support Help Us Follow Our Own Rules in Pediatric Acute Respiratory Distress Syndrome?
Computerized decision support in pediatric #ARDS may improve guideline compliance. Can #MachineLearning improve on this further? @drjonpelly and @cmhorvat discuss a new phase one clinical trial in this month’s @PedCritCareMed.