Pediatr Crit Care Me
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Pediatr Crit Care Me · Jul 2009
Multicenter StudyManagement of severely injured children in road accidents in France: impact of the acute care organization on the outcome.
To examine the impact of acute care management on outcome in children severely injured in road accidents. ⋯ The management in a more aggressive center for children admitted to TRR and monitored for ICP, when indicated, is associated with a better outcome. This could be explained by a more extensive experience in trauma management.
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Pediatr Crit Care Me · Jul 2009
Neuron-specific enolase and S-100B are associated with neurologic outcome after pediatric cardiac arrest.
To characterize the pattern of serum biochemical markers of central nervous system injury (neuron-specific enolase [NSE], S-100B, plasminogen activator inhibitor-1 [PAI-1]) after pediatric cardiac arrest and determine whether there is an association between biomarker concentrations and neurologic outcome. ⋯ The timing, intensity, and duration of serum NSE and S-100B biomarker concentration patterns are associated with neurologic and survival outcomes following pediatric cardiac arrest. Serum NSE concentrations at > or =48 hrs are associated with neurologic outcome, whereas serum S-100B levels at > or =48 hrs are associated with survival. Prospective analysis of these markers may help to predict outcomes and guide postresuscitative therapies.
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Pediatr Crit Care Me · Jul 2009
Clinical TrialEnteral feeding algorithm for infants with hypoplastic left heart syndrome poststage I palliation.
Infants with hypoplastic left heart syndrome (HLHS) experience a high incidence of growth failure in the postoperative period following stage I palliation. Because of an increased risk of necrotizing enterocolitis in this population, clinicians may be reluctant to initiate early enteral feedings. Published guidelines for initiating and advancing enteral feedings in this population are limited. ⋯ The use of an enteral feeding algorithm is a safe and effective means of initiating and advancing enteral nutrition in infants with HLHS following stage I palliation.
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Pediatr Crit Care Me · Jul 2009
Intravenous levetiracetam in critically ill children with status epilepticus or acute repetitive seizures.
Intravenous (IV) levetiracetam (LEV) is approved for use in patients older than 16 years and may be useful in critically ill children, although there is little data available regarding pharmacokinetics. We aim to investigate the safety, an appropriate dosing, and efficacy of IV LEV in critically ill children. ⋯ IV LEV was effective in terminating status epilepticus or acute repetitive seizures and well tolerated in critically ill children. Further study is needed to elucidate the role of IV LEV in critically ill children.
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Pediatr Crit Care Me · Jul 2009
Risk factors for central line-associated bloodstream infection in a pediatric cardiac intensive care unit.
To identify risk factors for central line-associated bloodstream infection (BSI) in patients receiving care in a pediatric cardiac intensive care unit. ⋯ Unscheduled medical admissions, presence of noncardiac comorbidities, extended device utilization, and specific medical therapies are independent risk factors for central line-associated BSI in patients receiving care in a pediatric cardiac intensive care unit.