An Sist Sanit Navar
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An Sist Sanit Navar · May 2012
Review[Monogenic human obesity: role of the leptin-melanocortin system in the regulation of food intake and body weight in humans].
Human obesity is a disorder of multifactorial origin in which genetic and environmental factors are involved. To understand the mechanisms regulating energy intake and fat accumulation in the body, it is important to study the genetic alterations causing monogenic obesity. ⋯ Previous studies have described mutations in leptin and its receptor, proopiomelanocortin and prohormone convertase 1 associated with human obesity of monogenic origin. The aim of this study is to provide an updated review of the main characteristics and functioning of the leptin-melanocortin system, and its implications and potentialities in regulating food intake and body weight.
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An Sist Sanit Navar · May 2012
Case Reports[Penetrating ascending aortic ulcer in an asymptomatic patient].
Penetrating aortic ulcer (PAU) has been defined as an atherosclerotic plaque ulceration that breaks the internal elastic lamina of the aorta, which may progress to a wall hematoma or aortic dissection in the case of blood seeping into the middle layer. Although PAU is commonly located in the descending aorta, the involvement of the ascending aorta can be fatal. Therefore, surgery is indicated even in asymptomatic patients presenting an ascending PAU. We report on an asymptomatic patient with ascending PAU referred for replacement of the ascending aorta with a composite prosthetic graft.
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An Sist Sanit Navar · May 2012
[Factors associated with willingness to be vaccinated against pandemic flu A/H1N1 in the adult population of the Health Department of Elche (Spain)].
To assess, in the general population, the information sources, attitudes and willingness to be vaccinated against pandemic influenza A/H1N1 in 2009. ⋯ Low acceptance of the pandemic vaccination and low perceived severity of influenza A/H1N1. Previous vaccination experience with seasonal flu creates a predisposition to immunization against A/H1N1. Although the media were the leading source of information during this period, the family doctor's influence on their decision to be vaccinated was significant.
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An Sist Sanit Navar · May 2012
[Prediction model for in-hospital admission in patients arriving in the emergency department].
To develop a prediction model for in-hospital admission to provide an almost "real time" determination of hospital beds needed, so as to predict the resources required as early as possible. ⋯ The in-hospital admission prediction model is a good and useful tool for predicting the in-hospital beds needed when patients arrive at the emergency department.
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An Sist Sanit Navar · May 2012
[Basic and advanced life support units in Spain: analysis of the current situation].
To describe the type and number of emergency care ambulances integrated in the Emergency Medical System in the Spanish autonomous communities and to calculate their relationship with the assigned population. ⋯ There are significant differences in the calculated rates of emergency care resources of autonomous regions over their population and area. No relation was found with the geodemographic idiosyncrasies of each territory. These differences could be caused by heterogeneity in the management of EMS or other factors not considered in this work.