Ann Trop Med Parasit
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Ann Trop Med Parasit · Dec 2003
Randomized Controlled Trial Clinical TrialThe effectiveness of 3, 5 or 7 days of albendazole for the treatment of Trichuris trichiura infection.
A randomized clinical trial was carried out to study the relationship between the duration of albendazole therapy, at 400 mg/day, and its effectiveness in the treatment of Trichuris trichiura infection. The 168 patients were treated for three (N=56), five (N=56) or seven (N=56) consecutive days. ⋯ The advantage of using the longer (5- or 7-day) regimens was most apparent among the patients who had heavy infections (at least 1000 Trichuris eggs/g faeces) when treated. It is therefore suggested that albendazole be given for at least 3 days to those with light infections and for 5-7 days to patients with heavy infections.