Chronic Dis Can
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Randomized Controlled Trial Multicenter Study
Acceptability of micronutrient sprinkles: a new food-based approach for delivering iron to First Nations and Inuit children in Northern Canada.
Iron deficiency anemia (IDA) is a significant public health problem among Canadian Aboriginal children. The objectives of this study were to determine the acceptability and safety of microencapsulated-iron sprinkles, a new powdered form of iron packaged in a single-serving sachet for prevention of IDA. A total of 102 non-anemic children aged 4 to 18 months from three communities were randomized to receive sprinkles containing 30 mg Fe/day (NR = 49) or placebo (NR = 53) for six months. ⋯ There were no differences in adherence, SF, anthropometric status or side effects between groups. Although there were no differences in hemoglobin (Hb) concentration and anemia prevalence from baseline to end and between groups, the Hb curve shifted to the right (increased) for the sprinkles group and to the left (decreased) for the placebo group. Sprinkles may provide a safe and acceptable option to the current standard of care (i.e. ferrous sulphate drops) for the provision of iron in Canadian Aboriginal populations.
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This study reports a comprehensive array of breast cancer statistics for Manitoba for a 40-year period. Data from the Manitoba Cancer Registry were combined with the provincial population-based registration file to determine trends in breast cancer incidence, prevalence and mortality rates, as well as survival and the probability of being diagnosed with breast cancer in the next 10 years. The age-standardized incidence rate of breast cancer increased by 0.99/100,000 women per year over the 40 years of follow-up (69.6/100,000 women in 1960, 109.9/100,000 women in 1999). ⋯ The probability of being diagnosed with breast cancer in the next 10 years increased the most for women 60 years of age. The breast cancer burden in Manitoba is rapidly evolving mainly because of the increasing incidence and the better survival of cases. Key words: breast neoplasms, incidence, prevalence, registries, vital statistics.