Psychosomatic medicine
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Psychosomatic medicine · Apr 2011
Comparative StudyModerating effects of moderate-intensity physical activity in the relationship between depressive symptoms and interleukin-6 in primary care patients.
To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be related to higher levels of the inflammatory marker IL-6; however, previous findings are inconsistent, possibly due to unidentified moderating factors. ⋯ Participation in moderate-intensity physical activity may buffer the risk of higher inflammation often associated with higher levels of depressive symptoms.