British medical bulletin
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Women now outnumber men in British medical schools. This paper charts the history of women in medicine and provides current demographic trends. ⋯ Further research is needed to explore the cost-effectiveness of existing and future interventions in this field.
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Antipsychotic medications are mainstays in the treatment of schizophrenia and a range of other psychotic disorders. ⋯ A focus on the different symptom domains of schizophrenia may lead to endophenotypic markers being identified, e.g. for negative symptoms and cognitive deficits (as well as for positive symptoms) that can promote the development of novel therapeutics, which will rationally target cellular and molecular targets, rather than just the dopamine 2 receptor. Future developments will target additional processes, including glutamatergic, cholinergic and cannabinoid receptor targets and will utilize personalized medicine techniques, such as pharmacogenetic variants and biomarkers allowing for a tailored and safer use of antipsychotics.