British medical bulletin
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British medical bulletin · Jul 2020
ReviewNon-insulin therapies in addition to insulin in Type 1 DM treatment.
Complications of Type 1 diabetes (T1DM) remain prevalent due to suboptimal glycaemic control despite advances in analogue insulin, its delivery and technological advances in glucose monitoring. Intensive insulin therapy is associated with hypoglycaemia and weight gain. Non-insulin-dependent glucose lowering strategies may provide a strategy in improving glycaemic control without hypoglycaemia and weight gain. ⋯ There is a need for larger clinical trials with SGLT2 inhibitors in T1DM and real world studies to clarify safety.
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British medical bulletin · Jul 2020
Arthroscopic superior capsular reconstruction versus latissimus dorsi transfer for irreparable rotator cuff lesions: a systematic review.
The present systematic review compared arthroscopic superior capsular reconstruction (ASCR) and latissimus dorsi transfer (ALDT) for the management of massive irreparable rotator cuff lesions. ⋯ Further comparative prospective and retrospective studies with longer follow-up could confirm which surgical procedure can lead to better outcomes with a lower complication rate.
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British medical bulletin · Jul 2020
ReviewThe potential application of artificial intelligence for diagnosis and management of glaucoma in adults.
Glaucoma is the most frequent cause of irreversible blindness worldwide. There is no cure, but early detection and treatment can slow the progression and prevent loss of vision. It has been suggested that artificial intelligence (AI) has potential application for detection and management of glaucoma. ⋯ There is a need to determine the external validity of deep learning algorithms and to better understand how the 'black box' paradigm reaches results.
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British medical bulletin · Jul 2020
ReviewHealth inequalities are worsening in the North East of England.
The North of England, particularly the North East (NE), has worse health (e.g. 2 years lower life expectancy) and higher health inequalities compared to the rest of England. ⋯ Research to understand and reduce health inequalities is needed particularly in the NE of England where reductions could have enhanced the impact.
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This review aims to provide information on outcomes of surgical procedures for soft tissue or bony glenoid and/or humeral abnormalities in case of posterior shoulder instability. ⋯ Future prospective studies should aim to establish the optimal treatment modalities for posterior shoulder instability.