Resp Care
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Preparation, submission, and presentation of an abstract are important facets of the research process, which benefit the investigator/author in several ways. Writing an abstract consists primarily of answering the questions, "Why did you start?" "What did you do?" "What did you find?" and "What does it mean?" A few practical steps in preparing to write the abstract can facilitate the process. This article discusses those steps and offers suggestions for writing each of an abstract's components (title, author list, introduction, methods, results, and conclusions); considers the advantages and disadvantages of incorporating a table or figure into the abstract; offers several general writing tips; and provides annotated examples of well-prepared abstracts: one from an original study, one from a method/device evaluation, and one from a case report.
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Explaining the meaning of the results to the reader is the purpose of the discussion section of a research paper. There are elements of the discussion that should be included and other things that should be avoided. Always write the discussion for the reader; remember that the focus should be to help the reader understand the study and that the highlight should be on the study data.
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Review Comparative Study
Alveolar mechanics in the acutely injured lung: role of alveolar instability in the pathogenesis of ventilator-induced lung injury.
With patients who have acute lung injury, respiratory function is routinely evaluated and the treatment may entail choices from various ventilatory strategies. The ventilatory strategies that have been used over the years are being replaced by newer protocols that represent improvements in patient treatment. However, the rationales for the various ventilatory strategies are largely empirical, because the physiology and mechanics of lung inflation are poorly understood. ⋯ We have researched alveolar histophysiology with animal experiments that combined a conventional histological approach with in vivo microscopy to assess alveolar dynamics during normal and disease-state ventilation. Our video and computer analyses document real-time changes of alveolar size and function, often in the same animal and in adjacent areas of the same lung. Our research indicates that, instead of supporting one theory of alveolar mechanics or another, the various behaviors reportedly exhibited by alveoli may be consistent and represent a continuum between normal alveolar function and the alveolar mechanics of acute lung injury.
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Calculation of total inspiratory resistance (Rtot) for patients on ventilatory support is typically based on measurement of airflow velocity and airway opening pressure during end-inspiratory occlusion by the inspiratory valve in the ventilator. Systematic error is introduced into Rtot measurements because the inspiratory valve closes over a period of time (not instantaneously, so gas continues to flow into the circuit while the valve is shutting) and because the circuit tubing is a distensible compartment between the occluding valve and the respiratory system. The Rtot-measurement error can be minimized with a rapidly-shutting occlusion valve positioned at the airway opening, or, alternatively, by mathematical correction that accounts for the valve-closure period and circuit tubing characteristics. ⋯ The Puritan Bennett 840 measures Rtot more accurately than the Puritan Bennett 7200. Our equations to mathematically correct Rtot measurements made with the PB7200 and PB840 are useful in settings where very accurate Rtot measurements are necessary.