Neurol Neurochir Pol
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Neurol Neurochir Pol · Mar 2012
Intraoperative magnetic resonance-guided frameless stereotactic biopsies - initial clinical experience.
We present our early experience in intraoperative magnetic resonance (iMRI)-guided stereotactic frameless biopsies with special regard to its safety, efficacy and diagnostic value. ⋯ Frameless stereotactic iMRI-guided brain tumour biopsy is a safe and diagnostically effective procedure. The use of iMRI might increase the diagnostic value and safety of stereotactic biopsy and positively influence its economic balance.
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Neurol Neurochir Pol · Mar 2012
Review[Pathogenetic justification of statin use in ischaemic stroke prevention according to inflammatory theory in development of atherosclerosis].
There is an inflammatory component in the pathogenesis of ischaemic stroke, which plays an important role in inducing atherothrombotic and embolic stroke. Statins, HMG-CoA (3-hydroxy-3-methyl-glutaryl-coenzyme A) reductase inhibitors are widely used in the primary and secondary prevention of ischaemic stroke. ⋯ Additional benefits from the use of statins result from their effect on the immune system. Increased risk of recurrent vascular episodes and risk of death after statin withdrawal in patients with vascular disorders is connected with termination of the anti-inflammatory effect of these drugs. The authors highlight that because of the anti-inflammatory effect of statins it is reasonable to use them in all patients at risk of ischaemic stroke, including those with atrial fibrillation.