Journal of clinical pathology
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Detection of plasmid-mediated AmpC in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis.
This study investigated the prevalence of plasmid-mediated AmpC production in selected clinical isolates of Escherichia coli, Klebsiella species and Proteus mirabilis, and compared the results of boronic acid disc screening with conventional susceptibility testing for the detection of AmpC-positive isolates. ⋯ The prevalence of plasmid-mediated ampC was high in the study population, and may be missed by conventional susceptibility testing methods. Inhibitor-based screening methods would improve detection of this emerging resistance phenotype.
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To derive the relationship for the difference between direct and indirect ion selective electrode measurements of serum sodium and the total protein concentration. ⋯ A linear regression equation for the relationship of the absolute difference between direct and indirect ion selective electrode measurements of serum sodium and the total protein concentration can be validly derived. However, due to the large spread of data around the regression line, such equations should not be employed to decide when to use direct electrodes instead of indirect electrodes in routine clinical laboratories.