Journal of clinical pathology
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The pathogenic role of disseminated intravascular coagulation (DIC) during septic shock is incompletely understood. ⋯ The course of human septic shock, particularly inhibition of activated fibrinolysis during DIC, may be independently associated with hyperlactataemia; therefore a coagulation/fibrinolysis imbalance may contribute to tissue hypoxygenation and ultimately thereby to demise.