Clin Exp Rheumatol
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To identify the socioeconomic status, disease activity and psychiatric disorders that contribute to the health-related quality of life (HRQOL) in systemic lupus erythematosus (SLE) patients. ⋯ HRQoL in SLE is influenced by disease activity and psychiatric disorders. Socioeconomic status has no direct influence on the quality of life of lupus patients, while disease activity has a direct impact on the quality of life. Anxiety and depression were significant predictors of poor HRQoL. Understanding how these factors are inter-related may help clinicians focus their assessments and develop strategies to improve the HRQoL of lupus patients.