J Rheumatol
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Randomized Controlled Trial Comparative Study Clinical Trial
Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs.
Pain was analyzed in patients with fibromyalgia (FM) in a randomized, double blind, crossover study using intravenous (i.v.) administration of different drugs. ⋯ FM diagnosed according to the American College of Rheumatology criteria seems to include patients with different pain processing mechanisms. A pharmacological pain analysis with subdivision into responders and nonresponders might be considered before instituting therapeutic interventions or research.