Gastroent Hepat Barc
The most recent articles from:
June 2002
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Gastroent Hepat Barc · Jun 2002
Case Reports Comparative Study[Early-onset acute toxic hepatitis induced by intravenous amiodarone administration].
Amiodarone is a widely used and effective long-term antiarrhythmic drug but with known adverse effects. Prolonged oral administration of this drug has been implicated in numerous hepatic lesions, ranging from isolated, asymptomatic transaminase elevation to fulminant, fatal liver failure. ⋯ The drug was withdrawn and laboratory findings progressively returned to normal over the following days. We analyze a possible mechanism of action for hepatotoxicity and highlight the importance of monitoring liver function in patients receiving this drug.