Gastroent Hepat Barc
The most recent articles from:
May 2004
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Gastroent Hepat Barc · May 2004
Case Reports[Wilson's disease with severe neurological manifestations: response to trientine plus zinc therapy].
In patients with Wilson's disease and neurological manifestations, treatment with D-penicillamine can cause worsening of neurological symptoms, usually in the first few weeks of treatment. Because the neurological damage can be severe and irreversible, the use of D-penicillamine is controversial, and several authors believe that it should be avoided. ⋯ We present the case of a 17 year-old boy with severe neurologic Wilson's disease that had first presented six years previously. The patient showed a complete recovery after six months of treatment with a combination of trientine and zinc acetate.