Hepatob Pancreat Dis
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Hepatob Pancreat Dis · Feb 2004
Comparative StudyChanges of plasma D(-)-lactate, diamine oxidase and endotoxin in patients with liver cirrhosis.
Plasma D(-)-lactate and diamine oxidase (DAO) can reflect patients' intestinal mucosal condition. We evaluated the changes of plasma D(-)-lactate, DAO and endotoxin activities and their significance in patients with liver cirrhosis. ⋯ The data suggest that both plasma D(-)-lactate and DAO activity are sensitive markers for early diagnosis of gut failure and endotoxemia in patients with liver cirrhosis. The impairment of intestinal barrier function may be one of the critical reasons for deterioration of liver cirrhosis.