World J Gastroentero
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To determine the clinical, analytical and endoscopic factors related to ischemic colitis (IC) severity. ⋯ The factors that can predict poor prognosis of IC are the absence of hematochezia, tachycardia and peritonism, anemia and hyponatremia and stenosis.
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World J Gastroentero · Aug 2006
Clinical TrialPharmacodynamic and kinetic effect of rabeprazole on serum gastrin level in relation to CYP2C19 polymorphism in Chinese Hans.
To observe the pharmacokinetics and pharmaco-dynamics of rabeprazole and compare serum gastrin concentrations in different CYP2C19 genotype groups. ⋯ In Chinese Han healthy people, the pharmacokinetics of rabeprazole are dependent on the CYP2C19 genotype status, but acid-inhibitory efficacy of rabeprazole and the gastrin level are not influenced significantly.
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To clarify the safety and feasibility of hepatectomy for huge hepatocellular carcinoma (HCC). ⋯ Hepatectomy for huge HCC is safe and effective. It should be used to treat patients with low surgical risks and resectable tumours.