World J Gastroentero
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World J Gastroentero · Jun 2007
Leptin treatment ameliorates acute lung injury in rats with cerulein-induced acute pancreatitis.
To determine the effect of exogenous leptin on acute lung injury (ALI) in cerulein-induced acute pancreatitis (AP). ⋯ Exogenous leptin attenuates inflamma-tory changes, and reduces pro-inflammatory cytokines, nitric oxide levels, and CD40 expression in cerulein-induced AP and may be protective in AP associated ALI.