Arch Ophthalmol Chic
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Arch Ophthalmol Chic · Oct 1982
Comparative StudyVisual evoked potential and pupillary signs. A comparison in optic nerve disease.
We measured the pupil cycle time, the relative afferent pupillary defect, and the pattern-reversal visual evoked potential (VEP) in 41 patients with unilateral anterior ischemic optic neuropathy (AION) and 24 patients with unilateral optic neuritis. We speculated that the relative afferent pupillary defect would match the VEP amplitude and that the pupil cycle time would correspond to the VEP latency. ⋯ In these two groups of patients with unilateral optic neuropathy, the most sensitive objective indicator of disease was the relative afferent pupillary defect. The least sensitive indicator was the pupil cycle time.
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Arch Ophthalmol Chic · Mar 1980
Randomized Controlled Trial Comparative Study Clinical TrialLack of side effects from topically administered 10% phenylephrine eyedrops. A controlled study.
A prospective double-blind study was designed to determine the systemic hypertensive effects of topically administered 10% aqueous buffered phenylephrine hydrochloride vs topically administered 1% aqueous tropicamide, a belladonna alkaloid devoid of vasopressor effect. One hundred persons received phenylephrine, while 50 persons received tropicamide. ⋯ Mean blood pressure and pulse rate dropped from baseline values in both groups at 5, 15, and 30 minutes after drug administration. There was no statistically significant difference between the experimental and control groups with respect to drug effect on either blood pressure or pulse rate throughout the study.
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Arch Ophthalmol Chic · Aug 1978
Randomized Controlled Trial Clinical Trial Controlled Clinical TrialAntiemetic effect of droperidol after ophthalmic surgery.
Postoperative nausea with emesis is an undesirable side effect of general anesthesia in patients who have undergone ophthalmic surgery. The antiemetic effect of intravenous droperidol (Inapsine) was measured in a double-blind, controlled study of 78 patients undergoing general (enflurane [Ethrane]) anesthesia for a variety of ophthalmic procedures. ⋯ No complications of droperidol administration were observed. Droperidol may be an effective antiemetic drug if used prophylactically in patients who receive general anesthesia for ophthalmic surgery.
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Convulsions developed in two patients after retrobulbar block. The amount of local anesthetic agent that was used was considerably less than the intravenous toxic dose in both cases. No retrobulbar hemorrhage resulted. The probable cause of seizures was inadvertent injection of local anesthetic directly to the CNS via the ophthalmic artery or its sheath.
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A 7-year-old girl developed bilateral ptosis, total ophthalmoplegia, and fixed, dilated pupils associated with bulbar paralysis and generalized weakness six days after she sustained a compound supracondylar fracture of the right humerus. Nerve conduction studies showed a facilitated muscle action potential after repetitive nerve stimulation. ⋯ Clostridium botulinum, type B, grew from cultures taken from the depths of the wound. The patient recovered fully with supportive care, and EEG abnormalities present during the acute phase of the illness disappeared.