American journal of physical anthropology
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Am. J. Phys. Anthropol. · Sep 2009
Brief communication: Paleohistopathological analysis of pathology museum specimens: can periosteal reaction microstructure explain lesion etiology?
The assertion that the microstructure of periosteal new bone formation can be used to differentiate between disease etiologies (Schultz: Yrbk Phys Anthropol 44 2001 106-147; Schultz: Identification of pathological conditions in human skeletal remains, 2nd ed. London: Academic Press 2003 73-109) was tested in a pilot-study, using diagnosed bone specimens from St George's Hospital Pathology Museum, London, UK. ⋯ Grenzstreifen, Polsters, and sinuous lacunae) deemed to be diagnostic of specific pathological conditions are of no specific diagnostic value, as they are encountered in pathological conditions of differing disease etiology. These results tie in with a previous investigation demonstrating a lack of diagnostic qualitative or quantitative characteristics seen in the macroscopic and radiographic appearance of periosteal reactions (Weston: Am J Phys Anthropol 137 2008 48-59).