Sarcoidosis Vasc Dif
-
Sarcoidosis Vasc Dif · Oct 2012
Multicenter Study Comparative StudyAre clinical features in Löfgren's syndrome-related erythema nodosum different from idiopathic erythema nodosum?
We retrospectively evaluated acute sarcoidosis (Löfgren's syndrome) patients diagnosed at 2 centers and compared the clinical features of Löfgren's syndrome (LS) related erythema nodosum (EN) to patients with idiopathic IEN who were diagnosed within the same time frame. ⋯ Apart from BHL, arthritis and/or arthralgia especially periarticular ankle inflammation is the feature which could be used to differentiate LS related EN from IEN. There is more need for steroids in LS patients and the symptoms quickly resolve with steroids.
-
Sarcoidosis Vasc Dif · Oct 2012
Comparative StudyHealth-related quality of life does not predict mortality in idiopathic pulmonary fibrosis.
Although health-related quality of life (HRQL) has recently been considered to be an important outcome in clinical trials of idiopathic pulmonary fibrosis (IPF), its relationship with survival is unknown. ⋯ There was no significant relationship between HRQL evaluated with the SGRQ and the subsequent mortality in IPF. The present negative result might suggest that HRQL is measuring an aspect other than one from physiological and functional impairment or disability.
-
Sarcoidosis Vasc Dif · Oct 2012
Comparative StudyFeasibility of cytological diagnosis of sarcoidosis with endobronchial US-guided transbronchial aspiration.
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has a high diagnostic value in sarcoidosis if the obtained histological specimen is indicative of a non-caseating epithelioid-cell granuloma. However, EBUS-TBNA in sacoidosis sometimes affords solely cytological specimens. ⋯ Cytological evaluation of the EBUS-TBNA specimens had higher sensitivity than histological evaluation alone for intrathoracic lymphadenopathy due to sarcoidosis. It should be recognized, however, that up to 6% of patients with thoracic malignancy may have sarcoid reaction in non-metastatic lymph nodes.
-
Sarcoidosis Vasc Dif · Oct 2012
Comparative StudyAnxiety and depression in sarcoidosis: the influence of age, gender, affected organs, concomitant diseases and dyspnea.
Heightened degrees of anxiety and depression are often found in patients suffering from sarcoidosis, but the reasons for that are unclear. Furthermore, age and gender differences of anxiety and depression in sarcoidosis have not been reported with reference to normative data. ⋯ The analysis of mental distress should take into account comparisons with normative values. Young patients deserve special social support. Dyspnea proved to be an important symptom in the prediction of anxiety and depression.
-
Sarcoidosis Vasc Dif · Oct 2012
Case ReportsChest wall shrapnel-induced beryllium-sensitization and associated pulmonary disease.
Chronic beryllium disease (CBD) is an exposure-related granulomatous disease mimicking sarcoidosis. Beryllium exposure-associated disease occurs mainly via inhalation, but skin may also be a source of sensitization. ⋯ A beryllium lymphocyte proliferation test, elemental analysis of removed shrapnel, and genetic studies were consistent with a diagnosis of CBD. This case demonstrates that retained beryllium-containing foreign bodies can be linked to a pathophysiologic response in the lung consistent with CBD.