Sarcoidosis Vasc Dif
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Sarcoidosis Vasc Dif · Mar 2016
Comparative StudyNuclear magnetic resonance spectroscopic analysis of salivary metabolome in sarcoidosis.
Sarcoidosis is a systemic granulomatous disease of unknown cause which has diverse clinical impacts, ranging from benign to very severe, which may therefore require systemic treatment. Only a few tools are currently available to monitor management in these patients. ⋯ This study showed that NMR metabolomics can discriminate saliva samples from sarcoidosis patients and controls. According to these preliminary results, saliva studies in sarcoidosis patients would be particularly useful to identify potentially relevant biomarkers. A study based on a larger number of patients at different stages of the disease or with treated patients is needed to assess the clinical relevance of NMR metabolomics in sarcoidosis.