The Medical journal of Australia
-
Ten acromegalics, 6 females and 4 males, aged 24 to 75, have been treated with bromocriptine (CB). Six patients responded clinically to CB: two subsequently escaped control, three have been treated continuously for from 14 to 32 months, and one withdrew because of side effects. ⋯ Three patients had severe illnesses during treatment and four patients were troubled by side effects. CB is useful in the treatment of acromegaly where other modalities are unsuitable.
-
Ten Caucasian patients with perhexiline maleate neurotoxicosis and weight loss are presented. Weight loss preceded symptomatic neuropathy which was detected on electromyography in one patient. Weight loss and neuropathy may be marked, but clinical improvement follows drug withdrawal.
-
A case of a 29-year-old man who developed a renal arteriovenous fistula after a gunshot injury is reported. The patient presented with renovascular hypertension associated with high putput cardiac failure, both of which were reversed by surgery.
-
Six trromboplastins commonly used for prothrombin time determinations were studied. Prothrombin times of patients who were receiving oral anticoagulant therapy varied widely, depending on the origin of the thromboplastins. The therapeutic range which is recommended with one thromboplastin is often quite different from that recommended with another, and as a result, the therapeutic ranges of different institutions may show no overlap. Management of patients and comparison of therapeutic results would be facilitated if all thromboplastins in use in Australia were standardized by comparison with the Australian Reference Thromboplastin.