The Medical journal of Australia
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Editorial Comment
The long term implications of fertility therapy for the health of women.
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To investigate the frequency and legitimacy of substantive changes to the research plans of published randomised controlled trials (RCTs) undertaken in Australia. ⋯ Changes to RCT study plans in Australia are both frequent and usually made appropriately blinded to treatment outcomes. However, the documentation of changes made to RCT protocols should be formalised to improve transparency.
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Editorial Comment
Where should we offer mass drug administration for trachoma?