The Medical journal of Australia
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To assess the impact of the transition from film to digital mammography in the Australian national breast cancer screening program. ⋯ The increased screen-detected cancer rate following the transition to digital mammography was not accompanied by a reduction in interval cancer detection rates.
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To assess the clinical impact on generally healthy older Australians of changing from the 2009 CKD-EPI (CKD-EPI2009) to the 2021 CKD-EPI (CKD-EPI2021) equation for calculating the estimated glomerular filtration rate (eGFR). ⋯ Using CKD-EPI2021 would yield higher eGFR values than the CKD-EPI2009, substantially reducing the proportion of older Australian adults classified as having CKD, without any overall difference in long term health outcomes for people reclassified to less advanced CKD stages. Using the CKD-EPI2021 could markedly reduce the number of referrals of generally healthy older adults to specialist nephrology services.
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To examine self-reported practices for obtaining ethics approval and reflections on ethics application processes among researchers who have conducted Aboriginal and Torres Strait Islander health and medical research. ⋯ Processes for obtaining ethics approval for Aboriginal and Torres Strait Islander health and medical research do not meet contemporary research needs and would be strengthened by streamlining ethics application processes, reducing time and cost barriers, and enhancing cultural appropriateness. We join calls for the establishment of state-based AHRECs in every jurisdiction, and a national Aboriginal and Torres Strait Islander human research ethics committee to review cross-jurisdictional research.