Arch Dermatol
-
Randomized Controlled Trial Comparative Study Clinical Trial
Pain associated with injection of botulinum A exotoxin reconstituted using isotonic sodium chloride with and without preservative: a double-blind, randomized controlled trial.
Botulinum A exotoxin is used for various indications, including the treatment of dynamic forehead lines. ⋯ Use of preservative-containing saline to reconstitute botulinum A exotoxin can significantly decrease patient discomfort on injection.