Berl Munch Tierarztl
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Berl Munch Tierarztl · Jan 2014
[Perioperative intensive-medical investigations regarding compatibility of the ketamine-azaperone-general anesthesia in pigs].
was observed. Perioperatively oxygen saturation was persistently high and mean arterial pressure was steady, too. An additional Ketamine administration caused a short tachycardia during operation. ⋯ Cortisol increased simultaneously with Ketamine and Azaperone before operation, but it remained at this level until the end of the determinations, parallel to the course of Norketamine, close to the maximum before anesthesia. The complex intensive-medical monitoring confirms that under real surgical conditions the counter-regulatory effects of both drugs equalize the respective cardiovascular and respiratory side effects. It is concluded also that the increase of cortisol is likely to be more a side effect of Ketamine/Norketamine than the expression of distress by surgical interventions or by wake-up reactions, and that an intoxication by additional Ketamine dosage or motoric disorders (i.e., catalepsis) can be excluded as undesired side effects of both drugs.