Minerva medica
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Small nucleolar RNA 47 promotes tumorigenesis by regulating EMT markers in hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is third leading cause of cancer-related death globally. Evidence suggest that small nucleolar RNAs (snoRNAs) have emerged as key regulators of tumor development and progression in HCC. However, the biological significance of snoRNAs in HCC remains unclear. ⋯ SnoRA47 may serve as a valuable biomarker and a potential therapeutic target for HCC.
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Review Meta Analysis
Bisphosphonates use and risk of gastric cancer: an updated meta-analysis of cohort and case-control studies.
Studies evaluating the association between bisphosphonates exposure and gastric cancer (GC) risk have reached inconsistent conclusions. The purpose of this updated meta-analysis was to assess whether bisphosphonates exposure were associated with an increased risk of GC. ⋯ Our meta-analysis found no overall association between GC risk and bisphosphonates use. Further studies with large sample size and more covariate adjustments are needed.