J Drugs Dermatol
-
Randomized Controlled Trial Comparative Study
Single blind, randomized, controlled trial of a lightening product with and without iontophoresis versus tretinoin and vehicle for hyperpigmentation.
Hyperpigmentation is a common concern and has many causes including lentigines and melasma. Currently available topical products for hyperpigmentation are limited by their potential for irritation, lack of demonstrated efficacy or regulatory concerns. ⋯ The investigational product was effective and may be better tolerated than tretinoin cream.