Ann Acad Med Singap
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Ann Acad Med Singap · Aug 2023
Poorer outcomes following COVID-19 infection for patients with depression: A cohort analysis in South Korea.
It remains unknown whether patients with pre-existing depressive conditions are at high risk of severe COVID-19. Therefore, this study aims to investigate the association between patients with pre-existing depressive conditions and severe COVID-19. ⋯ Moderate-to-severe depressive symptoms were associated with higher odds of severe COVID-19 events in both no and complete vaccination groups. Participants with depressive symptoms may be at higher risk of severe outcomes of COVID-19.
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Ann Acad Med Singap · Aug 2023
Fetal congenital heart diseases: Diagnosis by anatomical scans, echocardiography and genetic tests.
To determine the distribution of major fetal congenital heart diseases (CHDs) diagnosed antenatally during routine second-trimester obstetric anatomical scans in an unselected population at a single tertiary centre and to characterise and stratify risk factors, genetic diagnosis and long-term health at 4 years old. ⋯ Fetal echocardiograms accurately diagnose CHDs. Future studies should evaluate the roles of chromosomal microarray and next-generation sequencing in diagnosing CHD.