Arch Med Sci
-
The aim of the study was to examine the association between frailty and osteoarthritis. ⋯ There is both a correlation and a causal relationship between frailty and osteoarthritis, and frailty may be a potentially better response than age to osteoarthritis.
-
Regular physical activity (PA) is a recognized factor stimulating bone formation. In recent years, osteocytes have been shown to be involved in the metabolism of bone tissue in addition to osteoblasts and osteoclasts. The aim of the study was to analyze the effects of regular fitness training, sex hormones, and selected bone turnover markers on sclerostin levels in young women. ⋯ Our results show that regular fitness training, sex hormones, vitamin D, iPTH, β-CTx, and osteocalcin did not influence circulating sclerostin levels in young women.
-
The aim of the present study was to evaluate the diagnostic efficacy of different tendon reflexes in detecting diabetic peripheral neuropathy (DPN). ⋯ The assessment of tendon reflexes can be proposed as a test for screening diabetic polyneuropathy.
-
Cardiovascular disease is still a leading cause of death in Poland and across Europe. The aim of this study was to assess the attainment of the main treatment goals for secondary cardiovascular prevention in coronary patients with or without diabetes mellitus (DM) in Poland. ⋯ Great majority of Polish patients in secondary prevention do not achieve treatment goals. Although lipid goals attainment is better in DM and the rate of smokers is similar, the management of all risk factors needs to be improved.
-
Circulating microRNAs (miRNAs) are widely identified as promising and novel biomarkers for the diagnosis of human diseases. This study investigated the clinical value of miR-532-5p for asymptomatic carotid artery stenosis (CAS) patients and detected its predictive value for the occurrence of future cerebral ischaemic events (CIE). ⋯ The study suggests the potential clinical value of miR-532-5p for the early diagnosis of asymptomatic CAS patients. MiR-532-5p might have predictive value for the risk of future CIE in asymptomatic CAS patients.