B Acad Nat Med Paris
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B Acad Nat Med Paris · Aug 2021
Review[The COVID-19 battle at CHU Zhongnan and Leishenshan hospital: a summary of the global mobilization in China and reflections on the Wuhan experience].
The city of Wuhan, capital of Hubei, was the starting point of the Covid-19 epidemic and its doctors were led to develop novel strategies that have benefited the global fight in the country. But whatever strategies we hold up, the basic golden rule for controlling the pandemic has been early detection, reporting, isolation and treatment. The modalities of the battle were: swift action to block transmission with a vigorous, multifaceted response; resource allocation (a nationwide command system); Fangcang shelter hospitals; Broad community engagement: -provision of support via a volunteer network; People embraced behavioral change: -wearing masks and social distancing; Widespread testing: technical innovation; Science and technology curb the pandemic with research and digital technology; Free diagnosis and treatment for COVID-19. The success of our experience has provided valuable information to the international community in the fight against the pandemic.
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B Acad Nat Med Paris · Aug 2021
Review[Avian coronaviroses: Characteristics of epidemiological interest, in comparative medicine].
Coronavirus disease in veterinary medicine has been known since 1931 and is the cause of one of the most damaging diseases in poultry farming: avian infectious bronchitis (BIA). The characteristics most useful for the study of epidemiology are presented, in particular the very strong mutagenicity and the seasonality of infections with this virus. The control programs are based on numerous biosecurity measures applied as much to prevent viruses from spreading from sources of infection: biocontainment measures, as to measures to prevent contamination of uninjured herds: bioexclusion measures The control of avian coronaviruses is based mainly on vaccinations and because of the very strong mutagenic power of the virus, a race is regularly underway, to succeed in matching the different viruses frequently appearing in farms and vaccine viruses. This also obliges us to adapt each time and region by region the pool of vaccines used and the vaccination programs used.
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B Acad Nat Med Paris · Aug 2021
Review[From SARS, MERS to COVID-19: a journey to understand bat coronaviruses].
From the beginning of this century, three coronaviruses (CoVs) have caused severe human respiratory diseases, including severe respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and corona virus disease 2019 (COVID-19), which outbroke in 2002-2003, 2012 and 2019-2020, respectively. These viruses are three different species belonging to Coronaviridae family, Betacoronavirus genus. Discovery of closely-related CoVs in bats indicates that bats are natural reservoirs of these viruses. ⋯ However, these bat viruses seem to be low pathogenic in human ACE2 transgenic mice compared with the SARS-CoV-2. These results imply that these bat CoVs have potential interspecies transmission to other animals and humans. Our work highlights the necessity of preparedness for future emerging infectious diseases caused by these CoVs.