Bratisl Med J
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Penile block has been in use in penile surgery as a technique for perioperative analgesia for 25 years. The authors reintroduced penile block on the Department of Paediatric Anaesthetics and Intensive Care at the University Children's Hospital in Bratislava, Slovakia in June 2004 after 8 years. This prospective open observational study presents their experience with penile block for elective penile surgery in 96 paediatric patients (Tab. 3, Ref. 14).
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Randomized Controlled Trial
The use of controlled mild hypothermia and immune system status in patients with severe brain injury.
Severe brain injuries pose one of the most important problems on our health care because of their high morbidity and mortality. ⋯ Intensive treatment of intracranial hypertension fundamentally affects results of our treatment (Glasgow Outcome Score). The application of controlled mild hypothermia doesn't escalate the occurrence of extra cranial inflammatory complications after severe brain injury (Tab. 2, Fig. 11, Ref. 15).
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Randomized Controlled Trial
Correlation between the aPTT and clinical events in acute coronary syndromes treated with unfractionated heparin.
The primary objective of this study is to analyse relationship between activated partial thromboplastin time (aPTT) and clinical events in patients with unstable coronary artery disease. ⋯ The level of aPTT shows discordance with the onset of clinical events and is a weak predictor of outcomes (Tab. 2, Fig. 7, Ref 5).
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Monosodium glutamate (MSG) is the sodium salt of glutamic acid, widely spread in modern nutrition. Numerous recent studies have shown the existence of glutamic receptors on different nonneuronal cells, which among others also include lymphocytes and thymocytes. ⋯ These results indicate that MSG significantly modulates thymocyte proliferation by modulating the apoptosis rate of the cells. The temporal profile of Bcl-2 and Bax expression, after MSG treatment, suggest that down regulation of Bcl-2 protein and resulting change of Bcl-2/Bax protein ratio may be an important event in thymocyte apoptosis, triggered by MSG (Tab. 1, Fig. 3, Ref. 36).