Der Nervenarzt
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Over the last few years, the results from clinical studies and innovative radiological approaches have significantly altered the management of patients with cerebral venous thrombosis. In contrast to previously held beliefs, cerebral venous thrombosis is considered to be a relatively benign disease with an overall favourable prognosis. Mortality is <10%, and the vast majority of patients recover completely. ⋯ Non-invasive MR and CT angiography techniques have largely replaced conventional angiography for initial evaluation and follow-up examinations. Both methods have a high sensitivity for cerebral venous thrombosis. Local fibrinolytic therapy or other aggressive recanalizing methods can not be generally recommended.
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Recent discoveries about the central nervous system's response to injury and how patients reacquire behavioral capabilities by training have yielded promising new therapies for neurorehabilitation. This family of interventions is termed constraint-induced (CI) therapy and is essentially behavioral in nature. ⋯ Extending the principles to other consequences of stroke such as aphasia is examined. Constraint-induced therapy is shown to produce large changes in the organization and function of the brain,which emphasizes the significance of cortical reorganization and learning for neurorehabilitation.
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In cases of craniocerebral trauma there may be primary and secondary cerebral lesions. The principal goal of treatment is to minimize secondary cerebral trauma by optimized therapy. In the primary treatment phase monitoring of vital signs (blood pressure and respiration) is of crucial importance. CT diagnosis is followed by treatment of any increase in intracranial pressure by relief of hematomas, CSF drainage and appropriate intensive care measures.